Non-24-Hour Sleep-Wake Syndrome Following a Car Accident
The authors report the case of a 39-year-old sighted woman who displayed non-24-hour sleep–wake cycles following a car accident. The phase relationship between endogenous circadian markers such as plasma melatonin and 6-sulfatoxymelatonin rhythms and self-selected sleep times was abnormal. A laboratory investigation indicated that she was sensitive to bright light as a circadian synchronizer. MRI and brain CT scans were normal, but microscopic brain damage in the vicinity of the suprachiasmatic nucleus or its output pathways is plausible.
Boivin, D. B.; James, F. O.; Santo, Jonathan Bruce; Caliyurt, O.; and Chalk, C., "Non-24-Hour Sleep-Wake Syndrome Following a Car Accident" (2003). Psychology Faculty Publications. 10.