Presentation Title

EFFECT OF LOCAL HEAT APPLICATION DURING EXERCISE ON GENE EXPRESSION RELATED TO MITOCHONDRIAL HOMEOSTASIS

Advisor Information

Dustin, Slivka

Presentation Type

Poster

Start Date

26-3-2021 12:00 AM

End Date

26-3-2021 12:00 AM

Abstract

PURPOSE: Determine the impact of local muscle heating during endurance exercise on human skeletal muscle mitochondrial-related gene expression. METHODS: Fourteen subjects (25±6 yrs, 177±8 cm, 78±16 kg, and VO2 45±8 ml·kg-1·min-1) cycled with one leg heated (HOT) and the other kept at room temperature (CON). Skin and intramuscular temperatures were taken at Pre, Post-HOT, Post-Exercise and 4h-Post-Exercise. Muscle biopsies were taken from each leg at Pre and 4h-Post-Exercise for gene expression analyses. RESULTS: Intramuscular temperature increased within HOT (34.43±0.69ºC to 36.14±0.51ºC, pCONCLUSION: TFAM is enhanced by local heat application whereas other genes related to mitochondrial homeostasis were unaffected.

This document is currently not available here.

COinS
 
Mar 26th, 12:00 AM Mar 26th, 12:00 AM

EFFECT OF LOCAL HEAT APPLICATION DURING EXERCISE ON GENE EXPRESSION RELATED TO MITOCHONDRIAL HOMEOSTASIS

PURPOSE: Determine the impact of local muscle heating during endurance exercise on human skeletal muscle mitochondrial-related gene expression. METHODS: Fourteen subjects (25±6 yrs, 177±8 cm, 78±16 kg, and VO2 45±8 ml·kg-1·min-1) cycled with one leg heated (HOT) and the other kept at room temperature (CON). Skin and intramuscular temperatures were taken at Pre, Post-HOT, Post-Exercise and 4h-Post-Exercise. Muscle biopsies were taken from each leg at Pre and 4h-Post-Exercise for gene expression analyses. RESULTS: Intramuscular temperature increased within HOT (34.43±0.69ºC to 36.14±0.51ºC, pCONCLUSION: TFAM is enhanced by local heat application whereas other genes related to mitochondrial homeostasis were unaffected.