Presentation Title

Impact of Group III Activation During Prolonged Sitting with Mild Hypercapnia on Cardiovascular Function in Healthy Adults

Advisor Information

Dr. Song-Young Park

Presentation Type

Oral Presentation

Start Date

26-3-2021 12:00 AM

End Date

26-3-2021 12:00 AM

Abstract

IMPACTS OF GROUP III/IV ACTIVATION DURING PROLONGED SITTING WITH MILD HYPERCAPNIA ON CARDIOVASCULAR FUNCTION IN HEALTHY ADULTS

TeSean K. Wooden1, Elizabeth J. Pekas1, Michael F. Allen1, Cody P. Anderson1, and Song-Young Park1

1School of Health & Kinesiology, University of Nebraska at Omaha, Omaha, NE 68182

Prolonged sitting has been known to impair peripheral vascular function and often occurs in enclosed spaces with mild hypercapnic atmospheres. Our research group has previously confirmed the negative effects of prolonged sitting and found those effects were exacerbated with the addition of mild hypercapnia. Previous literature has attempted to negate the detrimental effects of prolonged sitting with activity breaks such as short period of walking and fidgeting but none have investigated the mechanism of Group III muscle afferent activation during those activity breaks on vascular function. Therefore, we sought to examine the impacts of Group III muscle afferent activation (passive movement) in healthy adults during prolonged sitting with mild hypercapnia. Fourteen healthy young adults participated in two experimental visits that consisted of sitting for 2.5 h in a control condition [mild hypercapnic condition (CO2 = 1500 ppm) sitting with no leg movement (NCH)] or a mild hypercapnic condition with passive movement during sitting (PCH). At both visits, measures of blood pressure (BP), brachial and popliteal artery endothelial function (FMD), arterial stiffness (PWV), augmentation index (AIx), Heart rate variability (HRV) and skeletal muscle oxygen utility in subjects. Significant group by time interactions (p

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Mar 26th, 12:00 AM Mar 26th, 12:00 AM

Impact of Group III Activation During Prolonged Sitting with Mild Hypercapnia on Cardiovascular Function in Healthy Adults

IMPACTS OF GROUP III/IV ACTIVATION DURING PROLONGED SITTING WITH MILD HYPERCAPNIA ON CARDIOVASCULAR FUNCTION IN HEALTHY ADULTS

TeSean K. Wooden1, Elizabeth J. Pekas1, Michael F. Allen1, Cody P. Anderson1, and Song-Young Park1

1School of Health & Kinesiology, University of Nebraska at Omaha, Omaha, NE 68182

Prolonged sitting has been known to impair peripheral vascular function and often occurs in enclosed spaces with mild hypercapnic atmospheres. Our research group has previously confirmed the negative effects of prolonged sitting and found those effects were exacerbated with the addition of mild hypercapnia. Previous literature has attempted to negate the detrimental effects of prolonged sitting with activity breaks such as short period of walking and fidgeting but none have investigated the mechanism of Group III muscle afferent activation during those activity breaks on vascular function. Therefore, we sought to examine the impacts of Group III muscle afferent activation (passive movement) in healthy adults during prolonged sitting with mild hypercapnia. Fourteen healthy young adults participated in two experimental visits that consisted of sitting for 2.5 h in a control condition [mild hypercapnic condition (CO2 = 1500 ppm) sitting with no leg movement (NCH)] or a mild hypercapnic condition with passive movement during sitting (PCH). At both visits, measures of blood pressure (BP), brachial and popliteal artery endothelial function (FMD), arterial stiffness (PWV), augmentation index (AIx), Heart rate variability (HRV) and skeletal muscle oxygen utility in subjects. Significant group by time interactions (p