Zhe Wang

Date of Award


Document Type


Degree Name

Master of Science (MS)


Computer Science

First Advisor

Dr. Guangshun Wang


As of late 2003, more than 500 antimicrobial peptides have been reported. However, the majority data of the antimicrobial peptides are scattered in the literature. In order to better understand the structure-function relationship of these peptides, and antimicrobial peptide database and analysis system (APD) was established based on an extensive literature search. The database contains detailed information for 525 peptides (498 antibacterial , 155 antifungal, 28 antiviral, and 18 antitumor). Based on the database, the system also provides database query, statistical data, prediction and peptide design functions. APD provides web-based interfaces that allow users to visit the system via a web browser from the Internet. This system was built using Red Hat Linux 7.2, MySQL database server, Apache web server and PHP script language. APD will provide a useful tool for the structure-function analysis of antimicrobial peptides. The system can be accessed at


A Thesis-Equivalent Project Presented to the Department of Computer Science and the Faculty of the Graduate College University of Nebraska In Partial Fulfillment of the Requirements for the Degree Master of Science University of Nebraska at Omaha. Copyright 2003 Zhe Wang.

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