Month/Year of Graduation


Degree Name

Bachelor of Science (B.S.)



First Advisor

Dr. Krishna Gundabolu


This retrospective study investigates the long-term management of Cerebral Venous Sinus Thrombosis (CVST) in 51 patients over a 3-month follow-up. The analysis covers demographics, risk factors, CVST presentation, associated diseases, thrombophilia, laboratory results, and antithrombotic treatments. CVST, a rare thrombosis of dural/cerebral sinuses, poses life-threatening risks with an annual incidence aligning with literature, notably affecting young individuals. Underlying causes range from rare disorders to common triggers, complicating diagnosis, especially during pregnancy. Imaging techniques aid diagnosis, with systemic anticoagulation preferred despite bleeding risks. Noteworthy findings include a higher incidence in women, predominantly presenting with headaches. Two cases of vaccine-induced immune thrombotic thrombocytopenia (VITT) post-Johnson & Johnson COVID-19 vaccination were identified. Limitations include retrospective design and incomplete records. The study enhances understanding of CVST demographics, clinical presentation, and treatments, with implications for early detection and management. Prospective, multi-center studies are recommended for validation and broader insights.

Available for download on Saturday, June 07, 2025