Author ORCID Identifier
Document Type
Article
Publication Date
5-31-2023
Abstract
Parkinson’s disease (PD) is associated with reduced coordination abilities. These can result either in random or rigid patterns of movement. The latter, described here as coordination rigidity (CR), have been studied less often. We explored whether CR was present in gait, quiet stance, and speech—tasks involving coordination among multiple joints and muscles. Kinematic and voice recordings were used to compute measures describing the dynamics of systems with multiple degrees of freedom and nonlinear interactions. After clinical evaluation, patients with moderate stage PD were compared against matched healthy participants. In the PD group, gait dynamics was associated with decreased dynamic divergence—lower instability—in the vertical axis. Postural fluctuations were associated with increased regularity in the anterior-posterior axis, and voice dynamics with increased predictability, all consistent with CR. The clinical relevance of CR was confirmed by showing that some of those features contribute to disease classification with supervised machine learning (82/81/85% accuracy/sensitivity/specificity).
DOI
https://doi-org.leo.lib.unomaha.edu/10.1080/00222895.2023.2217100
Journal Title
Journal of Motor Behavior
Volume
55
Issue
4
First Page
394
Last Page
409
Recommended Citation
Dotov, D., Cochen de Cock, V., Driss, V., Bardy, B., & Dalla Bella, S. (2023). Coordination Rigidity in the Gait, Posture, and Speech of Persons with Parkinson’s Disease. Journal of Motor Behavior, 55(4), 394–409. https://doi-org.leo.lib.unomaha.edu/10.1080/00222895.2023.2217100
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Comments
This is an Accepted Manuscript of an article published by Taylor & Francis in [JOURNAL TITLE] on [date of publication], available online: [Article DOI]