Document Type

Article

Publication Date

8-2011

Abstract

Background

Recent research demonstrated that intermittent claudication patients have increased gait variability prior to the onset of claudication. However, it is unknown if these patients experience additional gait adaptations after the onset of claudication. Thus, we sought to determine how gait variability is affected by claudication in an effort to contribute to improved clinical management.

Methods

Twenty-six intermittent claudication patients and 20 controls walked on a treadmill at self-selected speed; intermittent claudication patients were tested before (pain free) and after (pain) the onset of claudication. Variability of the ankle, knee, and hip joint angles was assessed using the largest Lyapunov exponent, standard deviation and coefficient of variation. Dependent t-tests were used to compare the pain free and pain conditions. Independent t-tests were used to compare intermittent claudication patients and controls.

Findings

Pain free and pain conditions were not significantly different for any of the parameters evaluated except the ankle. Compared to controls, patients had significantly greater values for the largest Lyapunov exponent in both conditions for all joints.

Interpretation

Gait variability was essentially the same before and after the onset of claudication at the knee and the hip, and was increased in both conditions compared to controls. This indicates altered cooperation between components of the locomotor system of intermittent claudication patients, likely due to the associated myopathy since differences were present even before the onset of claudication. This research helps provide essential biomechanical knowledge of intermittent claudication that contributes to improved clinical management.

Comments

NOTICE: this is the author’s version of a work that was accepted for publication in Clinical Biomechanics. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Clinical Biomechanics, [Vol. 26, Issue 7 (2011)] http://dx.doi.org/10.1016/j.clinbiomech.2011.03.005.

Journal Title

Clinical Biomechanics

Volume

26

Issue

7

First Page

729

Last Page

734

TitlePage.pdf (5 kB)
Title Page

FinalAppendix.pdf (95 kB)
Appendix

Figure1.pdf (41 kB)
Figure 1

Figure2.pdf (205 kB)
Figure 2

Final_Figure Legends.pdf (69 kB)
Figure Legends

Table 1.pdf (11 kB)
Table 1

Table 2.pdf (6 kB)
Table 2

Table 3.pdf (6 kB)
Table 3

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