Generating Transcriptomes for Denisova and Neanderthal

Advisor Information

Mark Pauley

Location

Dr. C.C. and Mabel L. Criss Library

Presentation Type

Poster

Start Date

6-3-2015 9:00 AM

End Date

6-3-2015 10:30 AM

Abstract

Beginning in 2010, the genomes of two ancestral human species, Neanderthal and Denisova, have been sequenced. These genomes have provided information about genetic diversity and genetic homology, approximate species age, genetic contribution of Neanderthals and Denisovans to modern-day humans, and modern day genetic relationships. While I am continuing to work on my project, I am assisting in the work that the Pauley group is doing in the collaboration with the Guda lab. I will help to validate the results of the BLAST of the human transcriptome against the Neanderthal and Denisova genomes. Next, I will work to write computer software to produce transcriptomes for Denisova and Neanderthal using sim4cc. For this, I will use the human transcriptome obtained from the National Center for Biotechnology Information, and the Denisovan and Neanderthal genomes, that have already been obtained by the Pauley group. This data will be provided to the Guda lab for further analysis.

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Mar 6th, 9:00 AM Mar 6th, 10:30 AM

Generating Transcriptomes for Denisova and Neanderthal

Dr. C.C. and Mabel L. Criss Library

Beginning in 2010, the genomes of two ancestral human species, Neanderthal and Denisova, have been sequenced. These genomes have provided information about genetic diversity and genetic homology, approximate species age, genetic contribution of Neanderthals and Denisovans to modern-day humans, and modern day genetic relationships. While I am continuing to work on my project, I am assisting in the work that the Pauley group is doing in the collaboration with the Guda lab. I will help to validate the results of the BLAST of the human transcriptome against the Neanderthal and Denisova genomes. Next, I will work to write computer software to produce transcriptomes for Denisova and Neanderthal using sim4cc. For this, I will use the human transcriptome obtained from the National Center for Biotechnology Information, and the Denisovan and Neanderthal genomes, that have already been obtained by the Pauley group. This data will be provided to the Guda lab for further analysis.