Advisor Information
Hesham Ali
Location
UNO Criss Library, Room 249
Presentation Type
Oral Presentation
Start Date
3-3-2017 2:45 PM
End Date
3-3-2017 3:00 PM
Abstract
With the recent advances in sequencing technology, we now have opportunities to study microbiomes associated with various environments. Recent studies have shown that the composition of microbiomes in our bodies and our environments play a significant role in impacting our health. Often referred to as the forgotten organ, 90% of human DNA is composed of bacterial microbiomes. In this study, we propose a graph-based systems biology approach to analyze the impact of microbiomes composition on the health and growth of organisms living in associated environments. We focus on two case studies; 1) The composition of soil microbiomes and how it impacts the growth of plants and their ability to fight diseases; and 2) The composition of microbiomes in fish gut and its impact on various growth parameters of three types of fish. The proposed model will explore features in each ecosystem including correlations among its microorganisms and their abundance levels. Early results show that there are clusters of microorganisms that are associated with heath and growth of plants and fish in both cases studies.
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A systems biology approach to analyze microbiome in soil and fish gut
UNO Criss Library, Room 249
With the recent advances in sequencing technology, we now have opportunities to study microbiomes associated with various environments. Recent studies have shown that the composition of microbiomes in our bodies and our environments play a significant role in impacting our health. Often referred to as the forgotten organ, 90% of human DNA is composed of bacterial microbiomes. In this study, we propose a graph-based systems biology approach to analyze the impact of microbiomes composition on the health and growth of organisms living in associated environments. We focus on two case studies; 1) The composition of soil microbiomes and how it impacts the growth of plants and their ability to fight diseases; and 2) The composition of microbiomes in fish gut and its impact on various growth parameters of three types of fish. The proposed model will explore features in each ecosystem including correlations among its microorganisms and their abundance levels. Early results show that there are clusters of microorganisms that are associated with heath and growth of plants and fish in both cases studies.