Measurement of Muscle Oxygen Saturation of the Gastrocnemius of Healthy Controls
Advisor Information
Sara Myers
Location
Dr. C.C. and Mabel L. Criss Library
Presentation Type
Poster
Start Date
2-3-2018 10:45 AM
End Date
2-3-2018 12:00 PM
Abstract
Peripheral Artery Disease (PAD) is a cardiovascular condition caused by blockages of the leg arteries that reduces blood flow. Claudication, a cramping pain or tiredness in the ischemic legs, is the most prevalent symptom associated with PAD that impairs patient walking ability. Oxygen delivery in the leg muscles is likely an important determinant of claudication and functional problems in these patients. We utilized a wireless sensor that determines oxygen saturation in the calf muscle to establish normal oxygen levels in healthy controls. Ten subjects (56.6 ± 8.9yrs; 177.86 ± 5.3cm; 80.82 ± 8.7kgs) performed three graded treadmill walking trials (2.0mph with 2% grade increase every two min). The trials were lengths of 105s, 231s, and 540s because patients with PAD have maximum walking times around one of those times. At rest, we found oxygen present in 53.24% of the hemoglobin molecules. Hemoglobin is the protein molecule that carries oxygen in the blood. At the start of exercise, oxygen saturation drops exponentially and remains at this low level until exercise stops. In recovery after exercise, oxygen saturation increased to 64.43%, above the baseline. We conclude that in healthy older individual’s exercise results in an immediate decrease in oxygen saturation that returns above pre exercise resting baseline shortly after stopping exercise.
Measurement of Muscle Oxygen Saturation of the Gastrocnemius of Healthy Controls
Dr. C.C. and Mabel L. Criss Library
Peripheral Artery Disease (PAD) is a cardiovascular condition caused by blockages of the leg arteries that reduces blood flow. Claudication, a cramping pain or tiredness in the ischemic legs, is the most prevalent symptom associated with PAD that impairs patient walking ability. Oxygen delivery in the leg muscles is likely an important determinant of claudication and functional problems in these patients. We utilized a wireless sensor that determines oxygen saturation in the calf muscle to establish normal oxygen levels in healthy controls. Ten subjects (56.6 ± 8.9yrs; 177.86 ± 5.3cm; 80.82 ± 8.7kgs) performed three graded treadmill walking trials (2.0mph with 2% grade increase every two min). The trials were lengths of 105s, 231s, and 540s because patients with PAD have maximum walking times around one of those times. At rest, we found oxygen present in 53.24% of the hemoglobin molecules. Hemoglobin is the protein molecule that carries oxygen in the blood. At the start of exercise, oxygen saturation drops exponentially and remains at this low level until exercise stops. In recovery after exercise, oxygen saturation increased to 64.43%, above the baseline. We conclude that in healthy older individual’s exercise results in an immediate decrease in oxygen saturation that returns above pre exercise resting baseline shortly after stopping exercise.