Advisor Information
Dr. Jennifer Yentes
Location
Dr. C.C. and Mabel L. Criss Library
Presentation Type
Poster
Start Date
2-3-2018 2:15 PM
End Date
2-3-2018 3:30 PM
Abstract
Imitation of COPD Breathing in Healthy, Young Individuals
Emma Leone, William Denton, Farahnaz Fallah Tafti, Jennifer Yentes, PhD Department of Biomechanics, University of Nebraska at Omaha, Omaha, NE Email: eleone@unomaha.edu
Chronic obstructive pulmonary disease (COPD) is not just a disease of the lungs; the disease affects the entire body. Patients with COPD have breathing and walking patterns that are less variable (more periodic) than controls. Locomotor respiratory coupling (LRC) exists in humans and is abnormal in patients with COPD. It is unknown if the breathing or the walking contributes to abnormal LRC in COPD. The purpose of this study was to mimic restrictive breathing in healthy young participants to induce LRC similar to those with COPD. Seventeen young adults (22.6±3.1 years) walked on a treadmill for six, six-minute conditions. Subjects walked at their preferred speed (PWS) and ±20% PWS. Subjects walked at each speed twice, once with normal breathing via a mask, and once with restrictive breathing via a customized plug inserted in the mask. A one-way repeated measures ANOVA was conducted to compare LRC differences between conditions within healthy young subjects. Healthy young adults were able to maintain normal LRC during restrictive breathing. Using existing data from healthy older adults (N=24) and patients with COPD (N=17), a repeated measures ANOVA was used to compare between groups. When compared to older adults and patients with COPD, young adults did not demonstrate similar LRC. Although most comparisons were not significantly different between healthy young and patients with COPD, qualitatively, they did not follow the same patterns. Based on the methods used, it was not possible to mimic the abnormal LRC found in patients with COPD.
Files over 3MB may be slow to open. For best results, right-click and select "save as..."
Imitation of COPD Breathing in Healthy, Young Individuals
Dr. C.C. and Mabel L. Criss Library
Imitation of COPD Breathing in Healthy, Young Individuals
Emma Leone, William Denton, Farahnaz Fallah Tafti, Jennifer Yentes, PhD Department of Biomechanics, University of Nebraska at Omaha, Omaha, NE Email: eleone@unomaha.edu
Chronic obstructive pulmonary disease (COPD) is not just a disease of the lungs; the disease affects the entire body. Patients with COPD have breathing and walking patterns that are less variable (more periodic) than controls. Locomotor respiratory coupling (LRC) exists in humans and is abnormal in patients with COPD. It is unknown if the breathing or the walking contributes to abnormal LRC in COPD. The purpose of this study was to mimic restrictive breathing in healthy young participants to induce LRC similar to those with COPD. Seventeen young adults (22.6±3.1 years) walked on a treadmill for six, six-minute conditions. Subjects walked at their preferred speed (PWS) and ±20% PWS. Subjects walked at each speed twice, once with normal breathing via a mask, and once with restrictive breathing via a customized plug inserted in the mask. A one-way repeated measures ANOVA was conducted to compare LRC differences between conditions within healthy young subjects. Healthy young adults were able to maintain normal LRC during restrictive breathing. Using existing data from healthy older adults (N=24) and patients with COPD (N=17), a repeated measures ANOVA was used to compare between groups. When compared to older adults and patients with COPD, young adults did not demonstrate similar LRC. Although most comparisons were not significantly different between healthy young and patients with COPD, qualitatively, they did not follow the same patterns. Based on the methods used, it was not possible to mimic the abnormal LRC found in patients with COPD.