EFFECT OF LOCAL HEAT APPLICATION DURING EXERCISE ON GENE EXPRESSION RELATED TO MITOCHONDRIAL HOMEOSTASIS
Advisor Information
Dustin, Slivka
Presentation Type
Poster
Start Date
26-3-2021 12:00 AM
End Date
26-3-2021 12:00 AM
Abstract
PURPOSE: Determine the impact of local muscle heating during endurance exercise on human skeletal muscle mitochondrial-related gene expression. METHODS: Fourteen subjects (25±6 yrs, 177±8 cm, 78±16 kg, and VO2 45±8 ml·kg-1·min-1) cycled with one leg heated (HOT) and the other kept at room temperature (CON). Skin and intramuscular temperatures were taken at Pre, Post-HOT, Post-Exercise and 4h-Post-Exercise. Muscle biopsies were taken from each leg at Pre and 4h-Post-Exercise for gene expression analyses. RESULTS: Intramuscular temperature increased within HOT (34.43±0.69ºC to 36.14±0.51ºC, pCONCLUSION: TFAM is enhanced by local heat application whereas other genes related to mitochondrial homeostasis were unaffected.
Scheduling Link
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EFFECT OF LOCAL HEAT APPLICATION DURING EXERCISE ON GENE EXPRESSION RELATED TO MITOCHONDRIAL HOMEOSTASIS
PURPOSE: Determine the impact of local muscle heating during endurance exercise on human skeletal muscle mitochondrial-related gene expression. METHODS: Fourteen subjects (25±6 yrs, 177±8 cm, 78±16 kg, and VO2 45±8 ml·kg-1·min-1) cycled with one leg heated (HOT) and the other kept at room temperature (CON). Skin and intramuscular temperatures were taken at Pre, Post-HOT, Post-Exercise and 4h-Post-Exercise. Muscle biopsies were taken from each leg at Pre and 4h-Post-Exercise for gene expression analyses. RESULTS: Intramuscular temperature increased within HOT (34.43±0.69ºC to 36.14±0.51ºC, pCONCLUSION: TFAM is enhanced by local heat application whereas other genes related to mitochondrial homeostasis were unaffected.
