Presenter Type
UNO Graduate Student (Masters)
Major/Field of Study
Biomechanics
Author ORCID Identifier
https://orcid.org/0009-0006-8668-4563
Advisor Information
Dr. Majid Jadidi
Location
CEC RM #201/205/209
Presentation Type
Poster
Poster Size
36x48
Start Date
22-3-2024 10:30 AM
End Date
22-3-2024 11:45 AM
Abstract
Introduction: Elastic fibers are key elements in various tissues such as skin, lungs, and arteries, offering stability, stretchability, and resilience. In the skin, they help prevent wrinkles, in the lungs, they aid in breathing, and in arteries, they store energy during heartbeats and ensure smooth blood flow. Production of these fibers peaks in late fetal stages and early infancy but generally stops after adolescence. However, over time, they can degrade due to aging or injury. Particularly in arteries, this degradation can lead to increased stiffness and a higher risk of cardiovascular diseases. Our team has investigated more than 1000 human femoropopliteal arteries (FPAs) and has observed a unique form of elastic fiber remodeling in human FPAs. This remodeling is characterized by long breaks in the external elastic lamina (EEL) of the FPAs. Often, these breaks are filled with thin, continuous elastic fibers. In this preliminary study, we aimed to examine these breaks and fibers, filling them in greater detail....
Breaks in Longitudinal Elastic Fibers of Human Femoropopliteal Arteries
CEC RM #201/205/209
Introduction: Elastic fibers are key elements in various tissues such as skin, lungs, and arteries, offering stability, stretchability, and resilience. In the skin, they help prevent wrinkles, in the lungs, they aid in breathing, and in arteries, they store energy during heartbeats and ensure smooth blood flow. Production of these fibers peaks in late fetal stages and early infancy but generally stops after adolescence. However, over time, they can degrade due to aging or injury. Particularly in arteries, this degradation can lead to increased stiffness and a higher risk of cardiovascular diseases. Our team has investigated more than 1000 human femoropopliteal arteries (FPAs) and has observed a unique form of elastic fiber remodeling in human FPAs. This remodeling is characterized by long breaks in the external elastic lamina (EEL) of the FPAs. Often, these breaks are filled with thin, continuous elastic fibers. In this preliminary study, we aimed to examine these breaks and fibers, filling them in greater detail....