Unraveling the Link Between Diet and Bifidobacteria Populations in the Gut of Nonhuman Primates

Presenter Type

UNO Graduate Student (Masters)

Major/Field of Study

Biology

Advisor Information

Dr.

Location

CEC RM #201/205/209

Presentation Type

Poster

Poster Size

36x48

Start Date

22-3-2024 1:00 PM

End Date

22-3-2024 2:15 PM

Abstract

Unraveling the Link Between Diet and Bifidobacteria Populations in the Gut of Nonhuman Primates

Mayowa J. Abioduna,b, Jordan B. Hernandeza,b,c, Cindy Schmidtd, Shivdeep S. Hayera,b, and Jonathan B. Claytona,b,c,e,f,g

aDepartment of Biology, University of Nebraska at Omaha, Omaha, NE, USA

bNebraska Food for Health Center, University of Nebraska-Lincoln, Lincoln, NE, USA

cDepartment of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, NE, USA

dLeon S. McGoogan Health Sciences Library, University of Nebraska Medical Center, Omaha, NE, USA

eDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, USA

fDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA

gPrimate Microbiome Project, University of Nebraska-Lincoln, Lincoln, NE, USA

The gut microbiome plays a crucial role in primate health. In mammals, the genus Bifidobacterium is known for its roles in digestion, immune modulation, and metabolite production. Members of the genus Bifidobacterium are also among the first microbes to colonize the gastrointestinal tract after birth. While environmental factors including diet, and habitat amongst many other factors influence the gut microbiome, their specific impact on modulating the population structure of resident microbes, particularly Bifidobacterium, remains unclear. Here we reviewed past and current literature to determine the state of knowledge regarding the relationship between the environment and Bifidobacterium spp. diversity and function in the gut of nonhuman primates (NHPs) utilizing major scientific literature databases: MEDLINE, CINAHL, PsycINFO, EMBASE, and Scopus. The terms used to search these databases included subject headings and keywords for “nonhuman primates” “and “bifidobacteria”. This search retrieved records for 226 unique publications. After the screening, we will organize the articles by NHP species, Environmental Status (Wild or Captive), Antibiotic Intervention (Yes/No), and Diet. In our review, we will discuss differences in Bifidobacterium spp. diversity across these categories and microbiome composition. We will highlight how studying Bifidobacterium spp. diversity relates to varying NHP conditions and offers new insights into the specific impacts and effects on gut microbiome structure and function. Understanding the influence of the environment on bifidobacteria populations could lead to dietary intervention strategies capable of improving the gut health of both NHPs and humans.

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Mar 22nd, 1:00 PM Mar 22nd, 2:15 PM

Unraveling the Link Between Diet and Bifidobacteria Populations in the Gut of Nonhuman Primates

CEC RM #201/205/209

Unraveling the Link Between Diet and Bifidobacteria Populations in the Gut of Nonhuman Primates

Mayowa J. Abioduna,b, Jordan B. Hernandeza,b,c, Cindy Schmidtd, Shivdeep S. Hayera,b, and Jonathan B. Claytona,b,c,e,f,g

aDepartment of Biology, University of Nebraska at Omaha, Omaha, NE, USA

bNebraska Food for Health Center, University of Nebraska-Lincoln, Lincoln, NE, USA

cDepartment of Genetics, Cell Biology, and Anatomy, University of Nebraska Medical Center, NE, USA

dLeon S. McGoogan Health Sciences Library, University of Nebraska Medical Center, Omaha, NE, USA

eDepartment of Food Science and Technology, University of Nebraska-Lincoln, Lincoln, NE, USA

fDepartment of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA

gPrimate Microbiome Project, University of Nebraska-Lincoln, Lincoln, NE, USA

The gut microbiome plays a crucial role in primate health. In mammals, the genus Bifidobacterium is known for its roles in digestion, immune modulation, and metabolite production. Members of the genus Bifidobacterium are also among the first microbes to colonize the gastrointestinal tract after birth. While environmental factors including diet, and habitat amongst many other factors influence the gut microbiome, their specific impact on modulating the population structure of resident microbes, particularly Bifidobacterium, remains unclear. Here we reviewed past and current literature to determine the state of knowledge regarding the relationship between the environment and Bifidobacterium spp. diversity and function in the gut of nonhuman primates (NHPs) utilizing major scientific literature databases: MEDLINE, CINAHL, PsycINFO, EMBASE, and Scopus. The terms used to search these databases included subject headings and keywords for “nonhuman primates” “and “bifidobacteria”. This search retrieved records for 226 unique publications. After the screening, we will organize the articles by NHP species, Environmental Status (Wild or Captive), Antibiotic Intervention (Yes/No), and Diet. In our review, we will discuss differences in Bifidobacterium spp. diversity across these categories and microbiome composition. We will highlight how studying Bifidobacterium spp. diversity relates to varying NHP conditions and offers new insights into the specific impacts and effects on gut microbiome structure and function. Understanding the influence of the environment on bifidobacteria populations could lead to dietary intervention strategies capable of improving the gut health of both NHPs and humans.