Date of Award

12-1-1990

Document Type

Thesis

Degree Name

Master of Arts (MA)

Department

Biology

First Advisor

Dr. William J. Kimberling

Abstract

Branchio-oto-renal (BOR) syndrome is an autosomal dominant disorder in which affected individuals may have conductive, sensorineural or mixed hearing loss, preauricular pits, structural defects of the outer, middle or inner ear, fistulas and cysts of the second bronchial arc and renal anomalies ranging from mild hypoplasia to complete agenesis. There is wide variation in expression of the syndrome and not all symptoms are present in all carriers of the gene. Less frequent systems (e.g. lacrimal duct stenosis) have been described.

Comments

A Thesis Presented to the Department of Biology and the Faculty of the Graduate College University of Nebraska In Partial Fulfillment of the Requirements for the Degree Master of Arts University of Nebraska at Omaha. Copyright 1990 Kimberly K. Comeau.

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