Presenter Information

Christina N. AngeliFollow

Advisor Information

Dustin Slivka

Location

Dr. C.C. and Mabel L. Criss Library

Presentation Type

Poster

Start Date

3-3-2017 10:45 AM

End Date

3-3-2017 12:00 PM

Abstract

BACKGROUND: Various physiological changes occur in the human body when ascending to altitude. Exposure to hypoxia increases heart rate and decreases arterial oxygen saturation (SaO2), with both changes being expedited during exercise. Incremental exercise in ambient conditions decreases muscle oxygenation, specifically with increasing intensity. Previous research has examined heart rate and SaO2 in response to normobaric versus hypobaric hypoxia. However, there is lack of research examining muscle oxygenation in response to these conditions. Therefore, additional research investigating acute responses to normobaric and hypobaric hypoxia during exercise is warranted. PURPOSE: To examine acute responses in arterial and muscle tissue oxygenation during incremental exercise in normobaric versus hypobaric hypoxia. METHODS: Eight recreationally active males and females between the ages of 19 and 45 will be recruited. Subjects will complete an incremental cycle test to volitional fatigue in three conditions in a randomized counter balanced order, normobaric normoxia (20.9% O2, 760 mmHg), normobaric hypoxia (14.3% O2, 760 mmHg) and hypobaric hypoxia (20.9% O2, 530mmHg). Two of the three trials will be conducted in an environmental chamber (Darwin, St. Louis, MO) to simulate normobaric normoxia at 350 m and normobaric hypoxia at 3094 m. The third trial will be conducted in Leadville, Colorado at 3094 m. Rating of perceived exertion, heart rate, blood oxygenation, respiration rate, muscle tissue oxygenation and whole body gases will be analyzed during the trials.

COinS
 
Mar 3rd, 10:45 AM Mar 3rd, 12:00 PM

Oxygen Transport in Normobaric versus Hypobaric Hypoxia

Dr. C.C. and Mabel L. Criss Library

BACKGROUND: Various physiological changes occur in the human body when ascending to altitude. Exposure to hypoxia increases heart rate and decreases arterial oxygen saturation (SaO2), with both changes being expedited during exercise. Incremental exercise in ambient conditions decreases muscle oxygenation, specifically with increasing intensity. Previous research has examined heart rate and SaO2 in response to normobaric versus hypobaric hypoxia. However, there is lack of research examining muscle oxygenation in response to these conditions. Therefore, additional research investigating acute responses to normobaric and hypobaric hypoxia during exercise is warranted. PURPOSE: To examine acute responses in arterial and muscle tissue oxygenation during incremental exercise in normobaric versus hypobaric hypoxia. METHODS: Eight recreationally active males and females between the ages of 19 and 45 will be recruited. Subjects will complete an incremental cycle test to volitional fatigue in three conditions in a randomized counter balanced order, normobaric normoxia (20.9% O2, 760 mmHg), normobaric hypoxia (14.3% O2, 760 mmHg) and hypobaric hypoxia (20.9% O2, 530mmHg). Two of the three trials will be conducted in an environmental chamber (Darwin, St. Louis, MO) to simulate normobaric normoxia at 350 m and normobaric hypoxia at 3094 m. The third trial will be conducted in Leadville, Colorado at 3094 m. Rating of perceived exertion, heart rate, blood oxygenation, respiration rate, muscle tissue oxygenation and whole body gases will be analyzed during the trials.