Advisor Information
Paul Davis
Location
Dr. C.C. and Mabel L. Criss Library
Presentation Type
Poster
Start Date
3-3-2017 10:45 AM
End Date
3-3-2017 12:00 PM
Abstract
The purpose of this clinical study is to determine the effectiveness of the updated treatment for acute osteomyelitis. This treatment plan consists of early transition from intravenous to oral antimicrobial therapy. The efficaciousness of these therapies were compared with post-discharge outcomes and complication rates. This study will utilize patient records during 2011 to 2016 from the University of Nebraska Medical Center and Children’s Hospital and Medical Center. The study includes patients aged from 1 month to 18 years for acute or unspecified osteomyelitis. Excluded patients are children with chronic osteomyelitis, hospitalization of ten or more days, patients with comorbid conditions that affect treatment or children with proneness to malabsorption of oral antibiotics. While data analysis is still being conducted for this project, some results are apparent. Initial data seems to suggest that patients undergoing earlier transition to oral antibiotics had similar outcomes than those with prolonged IV treatment. Furthermore, patients with Infectious Disease consults sustained better outcomes than those without. Because data analysis in not yet complete, no conclusions can be made with absolute certainty. However, initial analysis appears to suggest that in cases of pediatric osteomyelitis, oral antibiotic therapy is as effective as peripherally inserted central catheter, PICC, line therapy upon discharge. Children’s Hospital and Medical Center’s new guidelines should reflect this observation.
Outcomes of Early Transition from Intravenous to Oral Antimicrobial Treatment in Pediatric Osteomyelitis
Dr. C.C. and Mabel L. Criss Library
The purpose of this clinical study is to determine the effectiveness of the updated treatment for acute osteomyelitis. This treatment plan consists of early transition from intravenous to oral antimicrobial therapy. The efficaciousness of these therapies were compared with post-discharge outcomes and complication rates. This study will utilize patient records during 2011 to 2016 from the University of Nebraska Medical Center and Children’s Hospital and Medical Center. The study includes patients aged from 1 month to 18 years for acute or unspecified osteomyelitis. Excluded patients are children with chronic osteomyelitis, hospitalization of ten or more days, patients with comorbid conditions that affect treatment or children with proneness to malabsorption of oral antibiotics. While data analysis is still being conducted for this project, some results are apparent. Initial data seems to suggest that patients undergoing earlier transition to oral antibiotics had similar outcomes than those with prolonged IV treatment. Furthermore, patients with Infectious Disease consults sustained better outcomes than those without. Because data analysis in not yet complete, no conclusions can be made with absolute certainty. However, initial analysis appears to suggest that in cases of pediatric osteomyelitis, oral antibiotic therapy is as effective as peripherally inserted central catheter, PICC, line therapy upon discharge. Children’s Hospital and Medical Center’s new guidelines should reflect this observation.