Preparation of Theranostic Agents for Molecular Imaging
Presenter Type
UNO Undergraduate Student
Major/Field of Study
Biology
Other
Molecular and Biomedical Biology
Advisor Information
Bhavesh Patel/Suzanne Sollars
Location
MBSC302 - U
Presentation Type
Oral Presentation
Start Date
24-3-2023 1:00 PM
End Date
24-3-2023 2:15 PM
Abstract
The purpose of this project was to develop new and also improve upon current MRI contrast agents to increase the length of contrast enhancement. This would mean the agents stay in the body longer compared to MRI contrast agents currently in use. This is important because not as much contrast agent has to be used to achieve the same enhancement and this helps improves the diagnostic accuracy of the MRI scan. MRI with contrast is a vital diagnostic tool because it is superior at measuring and assessing tumors. Contrast helps detect even the smallest of tumors and MRI images with contrast are clearer and better quality than the images without contrast. The long term purpose of the project is to aid in image guided gene delivery. In the project, Gd and Eu were used as metals for their similar characteristics and ability to alter MRI properties while diethylenetriamine pentaacetate (DTPA) was used as a chelating agent.
Scheduling
9:15-10:30 a.m., 1-2:15 p.m.
Preparation of Theranostic Agents for Molecular Imaging
MBSC302 - U
The purpose of this project was to develop new and also improve upon current MRI contrast agents to increase the length of contrast enhancement. This would mean the agents stay in the body longer compared to MRI contrast agents currently in use. This is important because not as much contrast agent has to be used to achieve the same enhancement and this helps improves the diagnostic accuracy of the MRI scan. MRI with contrast is a vital diagnostic tool because it is superior at measuring and assessing tumors. Contrast helps detect even the smallest of tumors and MRI images with contrast are clearer and better quality than the images without contrast. The long term purpose of the project is to aid in image guided gene delivery. In the project, Gd and Eu were used as metals for their similar characteristics and ability to alter MRI properties while diethylenetriamine pentaacetate (DTPA) was used as a chelating agent.