Presenter Information

Vanessa GundersonFollow

Presenter Type

UNO Undergraduate Student

Major/Field of Study

Neuroscience

Other

Neuroscience major, minor in chemistry, pre-dental track

Advisor Information

Dr. Jonathan B. Clayton

Location

MBSC304 - U

Presentation Type

Oral Presentation

Start Date

24-3-2023 1:00 PM

End Date

24-3-2023 2:15 PM

Abstract

More individuals die from oral cancer every year than from melanoma, cervical cancer, and ovarian cancer in the United States. Further, the 5-year survival rate for oral cancer has remained stagnant for over forty years, which is almost unseen across any other form of cancer. This fact exposes that there is a major need to push for research, prevention, and education on oral cancer. To investigate this, a literature review was performed that looked at eight research studies and data from the Centers for Disease Control (CDC). This review revealed that without proper oral hygiene and care, one’s oral bacterial composition can alter to develop carcinogenic or cancer-causing taxa. The main factors putting individuals at risk for carcinogenic microbiota within the oral microbiome include microbiome homeostasis interruption, periodontal disease, smoking, chewing, excessive alcohol consumption, and poor oral hygiene. To combat this from occurring, the CDC recommends various daily habits and healthcare tips including daily brushing, a healthy diet, and regular dental visits. It is crucial to continue to push the boundaries of research to understand the complexities of how mechanisms intertwine within the oral microbiome to promote cancer development; this is so that preventative measures can be taken to increase the stagnant 5-year survival rate for oral cancer.

Scheduling

1-2:15 p.m., 2:30 -3:45 p.m.

COinS
 
Mar 24th, 1:00 PM Mar 24th, 2:15 PM

Role of Oral Microbiota in Cancer Development

MBSC304 - U

More individuals die from oral cancer every year than from melanoma, cervical cancer, and ovarian cancer in the United States. Further, the 5-year survival rate for oral cancer has remained stagnant for over forty years, which is almost unseen across any other form of cancer. This fact exposes that there is a major need to push for research, prevention, and education on oral cancer. To investigate this, a literature review was performed that looked at eight research studies and data from the Centers for Disease Control (CDC). This review revealed that without proper oral hygiene and care, one’s oral bacterial composition can alter to develop carcinogenic or cancer-causing taxa. The main factors putting individuals at risk for carcinogenic microbiota within the oral microbiome include microbiome homeostasis interruption, periodontal disease, smoking, chewing, excessive alcohol consumption, and poor oral hygiene. To combat this from occurring, the CDC recommends various daily habits and healthcare tips including daily brushing, a healthy diet, and regular dental visits. It is crucial to continue to push the boundaries of research to understand the complexities of how mechanisms intertwine within the oral microbiome to promote cancer development; this is so that preventative measures can be taken to increase the stagnant 5-year survival rate for oral cancer.